Filling materials in the various treatments differ in their degree of proximity. In cases where very fine lines are ignored, a substance with low level of lubrication will be used. As part of the wrinkle removal procedures, more prominent or for greater volume, a substance with high density will be used. Another method that also takes part in treatments is also offered alongside treatments Aesthetics, including the use of fat found in our body and is an excellent filler material, which helps in obtaining the desired volume. This is a method of wrinkle removal which is considered relatively simple and effective. Fat is a natural substance and its effect is for many years. On the other hand, the filling operation should be repeated several times, since usually only part of the injected filler survives and is absorbed directly into the tissue.